Scientists from Wuhan and the US were planning to create new coronaviruses that did not exist in nature by combining the genetic codes of other viruses, proposals show.
Documents of a grant application submitted to the US Defense Advanced Research Projects Agency (Darpa), leaked last month, reveal that the international team of scientists planned to mix genetic data of closely related strains and grow completely new viruses.
A genetics expert working with the World Health Organisation (WHO), who uncovered the plan after studying the proposals in detail, said that if Sars-CoV-2 had been produced in this way, it would explain why a close match has never been found in nature.
So far the closest naturally occurring virus to Sars-CoV-2 is a strain called Banal-52, which was reported from Laos last month and shares 96.8 per cent of the genome. Yet scientists expect a direct ancestor to be around a 99.98 per cent match – and none has been found so far.
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